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3.6out of 5

Erectile Dysfunction review

OnyxMD Ignite Review

OnyxMD Ignite is a compounded triple-action ED formula of sildenafil 70mg, tadalafil 20mg and apomorphine 4mg, from $9.72 a dose or $99 a month with a free consult and shipping, though its prices are not reconciled and the page lists no side effects or interactions.

Visit SiteUpdated November 2, 2026

OnyxMD Ignite at a glance

Our rating3.6 / 5
Best ForTriple-action ED with published doses
FormulaSildenafil 70mg, tadalafil 20mg, apomorphine 4mg
PriceFrom $9.72/dose or $99/mo
Onset / DurationClaimed 10 minutes · up to 36 hours
IncludedFree consult and discreet shipping
Availability47 states; not AK, MS or NJ

What is OnyxMD Ignite?

Ignite is OnyxMD's ED treatment, a compounded triple-action formula of sildenafil 70mg, tadalafil 20mg and apomorphine 4mg. It appears in our best ED treatment providers comparison. OnyxMD is run by Curated Care LLC, and telehealth is provided through Beluga Health, P.A.
Unlike many competitors, the page publishes the strengths. Sildenafil is described as the fast-acting component, tadalafil as the long-acting one, and apomorphine as supporting desire. The page claims onset in about 10 minutes and up to 36 hours of coverage, the latter attributed to tadalafil.
Care starts with a free online questionnaire or two-minute visit, reviewed by a licensed US physician who may or may not prescribe. Prescriptions are filled by Strive Pharmacy and EPIQ SCRIPTS. Service covers 47 states and excludes Alaska, Mississippi and New Jersey.
Pricing is where the page conflicts. Most buttons say from $9.72 a dose, while the closing section says from $99 a month, with no explanation of how many doses a month includes. The consult and shipping are called free, but the page does not say whether a subscription or prescription fee applies. It compares itself with Viagra at $70+ a pill and Cialis at $50+.
The page rates the product 4.93 from 1,800+ reviews, called verified without explanation, and claims no traditional ED pill touches the desire effect. No trial data for this combination is cited.

Pros

  • Publishes the strength of each ingredient
  • Free consult and discreet shipping; cancel anytime
  • Licensed US physician review in 47 states

Cons

  • Per-dose and monthly prices are not reconciled
  • No side effect or interaction information on the page
  • Two PDE5 inhibitors combined with no explanation; compounded, not FDA-approved
OnyxMD IgnitePer Dose: From $9.72
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How OnyxMD Ignite works

  1. Questionnaire. Complete a free online questionnaire or short visit.
  2. Physician review. A licensed US physician decides whether to prescribe.
  3. Pharmacy. A licensed pharmacy fills the prescription and ships discreetly.
  4. Ongoing. Cancel anytime; shipping is free.

Safety and what to know

PDE5 inhibitors such as sildenafil, tadalafil and vardenafil must never be combined with nitrate medicines (including nitroglycerin and “poppers”), because together they can cause a dangerous drop in blood pressure. The NIH’s NIDDK lists this interaction among the key cautions for ED medication. Common side effects include headache, flushing, a stuffy nose and indigestion; an erection lasting more than four hours needs emergency care.
The page does not explain why two PDE5 inhibitors are combined, and sildenafil 70mg plus tadalafil 20mg are not standard single-drug doses. It also lists no side effects, contraindications or interactions, so read the full safety information and ask the physician before ordering.
Apomorphine is better known as a Parkinson's disease medicine, and the page does not discuss its side effects, such as nausea or dizziness. Compounded products are not FDA-approved. The FDA’s compounding Q&A explains that the FDA does not verify their safety or effectiveness, and a registered pharmacy is not the same as an approved product.

OnyxMD Ignite pricing

Per DoseFrom $9.72
MonthlyFrom $99
Consult and ShippingFree
InsuranceNot required
The per-dose and monthly prices are not reconciled, and refund and shipping policies are linked but not shown. Confirm doses per month, billing terms and what happens if you are not prescribed.

Who OnyxMD Ignite is for

A good fit if

  • Want published ingredient strengths
  • Want a desire-supporting formula
  • Want to cancel anytime
  • Live in a covered state

Look elsewhere if

  • Take nitrate medication
  • Want a single, standard-dose PDE5 inhibitor
  • Live in Alaska, Mississippi or New Jersey
  • Want clear prices and refund terms

How OnyxMD Ignite compares

MEDVi offers a sublingual 4-in-1 blend with listed prices, and Omzo offers a 3-in-1 troche. OnyxMD stands out for publishing strengths, but combining two PDE5 inhibitors at these doses warrants a careful conversation with the physician.

OnyxMD Ignite FAQ

What is in OnyxMD Ignite?
Sildenafil 70mg, tadalafil 20mg and apomorphine 4mg in a compounded formula.
How much does Ignite cost?
From $9.72 a dose or from $99 a month, according to different parts of the page. Confirm at checkout.
Is Ignite FDA-approved?
No. OnyxMD states compounded products are not FDA-approved or verified for safety or effectiveness.
Where is OnyxMD available?
In 47 states, excluding Alaska, Mississippi and New Jersey.
Do I need a prescription?
Yes. A licensed US physician reviews your questionnaire and prescribes if appropriate.
Who should avoid it?
Anyone taking nitrates, and anyone a physician advises against PDE5 inhibitors.
Can I cancel anytime?
The page says cancel anytime, but refund terms are not shown.

Our verdict: 3.6 / 5

OnyxMD Ignite is a transparent-strength, triple-action ED option at a low per-dose price from a licensed-physician program. The unreconciled pricing, missing safety information and stacked PDE5 doses are the caveats. Discuss them with a clinician and confirm cost before you subscribe.
OnyxMD IgnitePer Dose: From $9.72
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Affiliate links used. Not medical advice — consult a licensed healthcare provider before starting any treatment.